I ran wearing the Injini socks yesterday. I put them on with no Bodyglide or any lubriant. They seemed to work realy well. My right big toe hurt a bit, and I think there might have been some fabric bunched around it. I am washing them and will wear them on my trail run December 23. I have read on the internet that some people will wear these, with another pair of socks over them-what is the purpose of the second pair of socks? To help preserve the life span of the Injini?